HTA in japan

Health Technology Assessment (HTA), a method of measuring product value and adjusting prices through Cost-Effectiveness Analysis (CEA), was introduced in Japan in 2019. Information about HTA and its process, CEA guidelines and results of previous assessments are available in Japanese and English on the C2H official website.

Global manufactures are often well prepared for their European HTA submissions and expect to be able to accomodate their Japanese HTAs with minimum modifications. Other manufactures are trying to start their CEA development from scratch by referring to the C2H guidelines.

our service

Healthcare to All (H2A) is specialized in CEA developmet, including not only CEA itself, but also real world evidence (RWE), systematic literature review (SLR) and patient reported outcomes (PRO). We offer complete support in HTA by collaborating with international and regional topic specific experts. H2A also supports development of a strategic HTA preparation plan.

Health Economics and Outcomes Research (HEOR) itself is an effective communication tool for optimizing market access. H2A often collaborates with stakeholders in strategic evidence planning, evidence generation, and evidence delivery. For instance, H2A works with medical professionals in evidece generation that can submitted to peer reviewed journals and further to be used as reference material in technical fee reimbursement applications and clinical practice guidelines.

Our deliverables in HTA and HEOR are tailored to meet appropriate quality levels required by target audiences such as the Ministry of Health (MHLW) and international journals. Our projecs have 1) appropriate HEOR methodologies that meet the latest international standards, 2) reflect local clinical practice, and 3) have realistic plans that meet business schedules.

project example

A Preliminary HTA preparation plan

Types of client: A manufacturer who already went through a HTA or a complete HTA preparation in other countries, and is planning Japan HTA preparation

Required resources: product information, launch plan, HTA preparation materials and HTA dossier prepared for other countries

Research methods: desk research (, and interviews TBD)

Deliverables: 1) Japan HTA overview, 2) Assessments on the existent CEA, 3) suggestions for next steps

Project delivery: Kick-off meeting, Weekly meetings with Q&A sessions, a final presentation (to the internal stakeholders upon request)

Please also visit other pages, such as Market Access page and team page. We will set up one hour free meeting to understand your needs and to tailor your project.